Anti Aldh1A1 Antibody
- Article
- Anti Aldh1A1 Antibody
- Product Number
- R1706-2
- Supplier
- Huabio
- Size
- 100 ul
- Description
- Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde, metabolism of corticosteroids, biogenic amines and neurotransmitters, and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Application
- FC, IF, IHC-P, WB
- Host
- Rabbit
- Species reactivity
- Human, Mouse, Rat
- Conjugate
- Unconjugated
- Immunogen
- Recombinant protein within human Aldh1A1 aa 1-160/501.
- Molecular Weight
- 55 kDa
- Synonyms
- acetaldehyde dehydrogenase 1; ALDC; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic; ALDH class 1; ALDH1; ALDH11; ALDH-E1; ALHDII; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; HEL12; HEL-9; HEL-S-53e; PUMB1; RALDH 1; RALDH1; retinal dehydrogenase 1; retinaldehyde dehydrogenase 1; Ahd; Ahd-; Ahd2; Ahd-2; alcohol dehydrogenase family 1, subfamily A1; alcohol dehydrogenase family 1, subfamily A2; ALD; aldehyde dehydrogenase 1, liver cytosolic (class 1); aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase, cytosolic; Aldh1a2; E1; Ral; aldehyde dehydrogenase 1, subfamily A1; aldehyde dehydrogenase 1A1; aldehyde dehydrogenase 2; aldehyde dehydrogenase family 1, subfamily A1; Aldh2
- Unigene ID
- 216
- Gene Symbols
- ALDH1A1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
Size: 100 ul
389.00 CHF