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CD45 antibody [30-F11] (Biotin...

Article
CD45 antibody [30-F11] (Biotin)
Product Number
GTX00456-100UG
Supplier
GeneTex
Size
100 ug
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Category
Antibodies
Product Group
Monoclonal Antibodies
Application
FACS
Host
Rat
Species reactivity
Mouse
Conjugate
Biotin
Clone ID
30-F11
Formulation
10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.
Immunogen
Mouse thymus or spleen
Synonyms
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, c polypeptide; receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen; Leukocyte common antigen
Unigene ID
5788
Gene Symbols
PTPRC
Shipping Temperature
BLUE ICE
Supplier URL
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