Anti Cytokeratin 17 Antibody
- Article
- Anti Cytokeratin 17 Antibody
- Product Number
- 0407-4
- Supplier
- Huabio
- Size
- 100 ul
- Description
- Cytokeratin 17 may play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Application
- FC, IF, IHC-P, WB
- Host
- Rabbit
- Species reactivity
- Human, Mouse, Rat
- Conjugate
- Unconjugated
- Immunogen
- Synthetic peptide within Human Cytokeratin 17 aa 383-432 / 432.
- Molecular Weight
- 48 kDa
- Synonyms
- 39.1; CK-17; cytokeratin-17; K17; keratin 17, type I; keratin, type I cytoskeletal 17; PC; PC2; PCHC1; keratin complex 1, acidic, gene 17; Krt1-1; Krt1-17; Ka17; type I keratin KA17; Keratin-17
- Unigene ID
- 3872
- Gene Symbols
- KRT17
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
Size: 100 ul
389.00 CHF