Anti DDB1 Antibody
- Article
- Anti DDB1 Antibody
- Product Number
- R1706-21
- Supplier
- Huabio
- Size
- 100 ul
- Description
- Damaged DNA binding protein (DDB) is a heterodimer composed of two subunits, p127 and p48, which are designated DDB1 and DDB2, respectively. The DDB heterodimer is involved in repairing DNA damaged by ultraviolet light. Specifically, DDB, also designated UV-damaged DNA binding protein (UV-DDB), xeroderma pigmentosum group E binding factor (XPE-BF) and hepatitis B virus X-associated protein 1 (XAP-1), binds to damaged cyclobutane pyrimidine dimers (CPDs). Mutations in the DDB2 gene are implicated as causes of xeroderma pigmentosum group E, an autosomal recessive disease in which patients are defective in nucleotide excision DNA repair. XPE is characterized by hypersensitivity of the skin to sunlight with a high frequency of skin cancer as well as neurologic abnormalities. The hepatitis B virus (HBV) X protein interacts with DDB1, which may mediate HBx transactivation.
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Application
- FC, IF, IHC-P, WB
- Host
- Rabbit
- Species reactivity
- Human, Mouse, Rat
- Conjugate
- Unconjugated
- Immunogen
- Recombinant protein within Human DDB1 aa 151-560 / 1,140.
- Molecular Weight
- 127 kDa
- Synonyms
- damage-specific DNA binding protein 1, 127kDa; DDB p127 subunit; DDBA; DNA damage-binding protein 1; DNA damage-binding protein a; HBV X-associated protein 1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; UV-DDB1; WHIKERS; XAP1; XAP-1; xeroderma pigmentosum group E-complementing protein; XPCE; XPE; XPE-BF; XPE-binding factor; 127kDa; AA408517; damaged-DNA recognition protein 1; damage-specific DNA-binding protein, DNA repair; p127-Ddb; p127-Ddb1; Damage-specific DNA-binding protein 1
- Unigene ID
- 1642
- Gene Symbols
- DDB1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
Size: 100 ul
389.00 CHF