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Anti Fatty Acid Synthase Antib...

Article
Anti Fatty Acid Synthase Antibody
Product Number
R1706-8
Supplier
Huabio
Size
100 ul
Description
Fatty acid biosynthesis is mediated by seven catalytic enzymes and an acyl carrier protein (ACP), to which various acyl intermediates are covalently attached. Fatty Acid Synthase (FAS) is the anabolic enzyme that contains the seven unique catalytic sites and mediates the conversion of acetyl-CoA and malonyl-CoA, in the presence of the cofactor NADPH, into long-chain saturated fatty acids, such as palmitate. Human Fatty Acid Synthase cDNA encodes a 2,504 amino acid protein. Catalytically active Fatty Acid Synthase is a homodimer. Human Fatty Acid Synthase mRNA is variably expressed with abundant levels present in brain, lung and liver. Fatty acid synthetic metabolism is abnormally elevated in tumor cells and may support cell growth or survival of malignant cancers.
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
IF, IHC-P, WB
Host
Rabbit
Species reactivity
Human, Mouse, Rat
Conjugate
Unconjugated
Immunogen
Recombinant protein within human Fatty Acid Synthase aa 801-1050.
Molecular Weight
273 kDa
Synonyms
FAS; fatty acid synthase; OA-519; SDR27X1; short chain dehydrogenase/reductase family 27X, member 1; type I fatty acid synthase; A630082H08Rik; F; type I FAS
Unigene ID
2194
Gene Symbols
FASN
Shipping Temperature
BLUE ICE
Supplier URL
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