This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]
Category
Antibodies
Product Group
Recombinant Antibodies
Application
WB
Host
Rabbit
Species reactivity
Human, Mouse
Conjugate
Unconjugated
Clone ID
GT1214
Formulation
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen
A synthesized peptide derived from human JAK2.
Synonyms
JAK-2; Janus kinase 2 (a protein tyrosine kinase); JTK10; tyrosine-protein kinase JAK2; Janus kinase 2