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Anti Tyrosine Hydroxylase Anti...

Article
Anti Tyrosine Hydroxylase Antibody
Product Number
R1706-18
Supplier
Huabio
Size
100 ul
Description
The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson's disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
FC, IF, IHC-P, WB
Host
Rabbit
Species reactivity
Human, Mouse, Rat
Conjugate
Unconjugated
Immunogen
Synthetic peptide within Human Tyrosine Hydroxylase aa 1-50 / 528.
Molecular Weight
58 kDa
Synonyms
dystonia 14; DYT14; DYT5b; TYH; tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; The
Unigene ID
7054
Gene Symbols
TH
Shipping Temperature
BLUE ICE
Supplier URL
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