Anti CD31 (Ms,Sw) from Rat (SZ...
- Article
- Anti CD31 (Ms,Sw) from Rat (SZ31) for mouse FFPE tissue
- Product Number
- DIA-310
- Supplier
- Dianova (Biozol)
- Size
- 500 ul
- Description
- Antibody clone SZ31 is the first antibody which reacts specifically with murine CD31 in formalin-fixed paraffin-embedded tissue sections. Clone SZ31 shows no cross-reactivity to human CD31. Outstanding specificity of clone SZ31 has been confirmed in more than 200 citations (CiteAB). CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1) is expressed constitutively on the surface of embryonic and adult endothelial cells. It is also expressed on cell surfaces of monocytes, neutrophils, platelets and certain T-cell subsets. It has been detected on bone marrow-derived hematopoetic stem cells and embryonic stem cells. Cluster of Differentiation 31 (CD31) is a 130kDa integral membrane glycoprotein and as a member of the immunoglobulin superfamily involved in the mediation of cell-to-cell adhesion. CD31-mediated endothelial cell-cell interactions play a major role in angiogenesis. Studies have shown CD31 to be a superior marker in human angiogenesis, which reportedly predicts tumor recurrence. Pathophysiological studies of CD31 in murine model systems had limitations because standard formalin-fixed sections were excluded. The clone SZ31 (Anti-CD31) eliminates these restrictions by allowing high quality immunohistochemical analysis of standard formalin-fixed paraffin sections in mice.
- Category
- Antibodies
- Product Group
- Monoclonal Antibodies
- Application
- ICC, IF, IHC, IHC-Fr, IHC-P, WB
- Host
- Rat
- Species reactivity
- Mouse, Other Insect / Arthropod, Porcine
- Conjugate
- Unconjugated
- Clone ID
- SZ31
- Immunogen
- Murine amino acid fragment (amino acids 610-681 of mouse CD31)
- Synonyms
- C85791; Cd31; Pecam; PECAM-1; platelet endothelial cell adhesion molecule
- Unigene ID
- 18613
- Gene Symbols
- Pecam1
- Shipping Temperature
- RT
- Supplier URL
- Visit supplier product page