FITC-Compatible Human CD19 Pro...
- Article
- FITC-Compatible Human CD19 Protein (CD1-HM119F)
- Product Number
- CD1-HM119F-100UG
- Supplier
- Kactus Bio
- Size
- 100 ug
- Description
- CD19 is a B-lineage-specific transmembrane glycoprotein, the expression of which is maintained on more than 95% B-cell malignancies. This strict lineage restriction makes CD19 an ideal target for immune therapies using chimeric antigen receptors (CARs). T cells engineered to express a chimeric antigen receptor (CAR) against CD19 have recently been FDA approved for the treatment of relapsed or refractory large B-cell lymphoma. Despite the success and curative potential of CD19 CAR T cells, several reports describing disease relapse due to antigen loss are now emerging.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Proteins
- Purity
- >95%
- Formulation
- Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
- Molecular Weight
- The protein has a predicted MW of 60.1 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Bis-Tris PAGE result.
- Synonyms
- B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12
- Shipping Temperature
- RT
- Supplier URL
- Visit supplier product page
