Human HLA-A*02:01&B2M&P53 R175...
- Article
- Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein (MHC-HM415T)
- Product Number
- MHC-HM415T-100UG
- Supplier
- Kactus Bio
- Size
- 100 ug
- Description
- p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Proteins
- Purity
- >95%
- Formulation
- Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
- Molecular Weight
- The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
- Synonyms
- beta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin; IMD43
- Unigene ID
- 567
- Gene Symbols
- B2M
- Shipping Temperature
- RT
- Supplier URL
- Visit supplier product page
