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Human HLA-G&B2M&Peptide (RIIPR...

Article
Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CT)
Product Number
HLG-HM41CT-100UG
Supplier
Kactus Bio
Size
100 ug
Description
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
Category
Proteins, Peptides and Small Molecules
Product Group
Proteins
Purity
>95%
Formulation
Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Molecular Weight
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Synonyms
beta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin; IMD43; HLA G antigen; MHC class I antigen G
Unigene ID
567
Gene Symbols
B2M
Shipping Temperature
RT
Supplier URL
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