SPY505-DNA is a bright green & non toxic live cell nuclear stain based on SPY™ dyes series. Its optimized structure allows quick labeling of DNA in live & fixed cells with high specificity and very low background. SPY505-DNA stains the nuclei of live or fixed cells without the need for genetic manipulation or overexpression of fluorescent proteins. Its absorbance and emission are similar to fluorescein or Alexa488™. SPY505-DNA enables multicolor imaging with SPY555, SPY595, SPY650, SPY700, SiR, RFP or mcherry. SPY505-DNA can be imaged with standard fluorescein (FITC) or YFP filtersets. It can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue.
