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anti FGF8 antibody

Article
anti FGF8 antibody
Product Number
ARG58580-50UG
Supplier
Arigo Biolaboratories
Size
50 ug
Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
IHC-P, WB
Host
Rabbit
Species reactivity
Human, Rat
Conjugate
Unconjugated
Formulation
0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
Immunogen
Synthetic peptide corresponding to aa. 163-185 of Human FGF8. (FMKRLPRGHHTTEQSLRFEFLNY)
Synonyms
AIGF; androgen-induced growth factor; FGF-8; fibroblast growth factor 8; fibroblast growth factor 8 (androgen-induced); HBGF-8; heparin-binding growth factor 8; HH6; KAL6
Unigene ID
2253
Gene Symbols
FGF8
Shipping Temperature
BLUE ICE
Supplier URL
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