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14-3-3 epsilon antibody [AT4F8...

Article
14-3-3 epsilon antibody [AT4F8]
Product Number
GTX57563-100UL
Supplier
GeneTex
Size
100 ul
Description
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
Category
Antibodies
Product Group
Monoclonal Antibodies
Application
ICC, IF, WB
Host
Mouse
Species reactivity
Human, Mouse
Conjugate
Unconjugated
Clone ID
AT4F8
Immunogen
The clone AT4F8 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-5 epsiilon protein.
Synonyms
14-3-3 epsilon; 14-3-3 protein epsilon; 14-3-3E; epididymis luminal protein 2; HEL2; KCIP-1; MDCR; MDS; mitochondrial import stimulation factor L subunit; protein kinase C inhibitor protein-1; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Unigene ID
7531
Gene Symbols
YWHAE
Shipping Temperature
BLUE ICE
Supplier URL
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