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3-Methyladenine

Article
3-Methyladenine
Product Number
AC-1002-0025
Supplier
Life Sensors
Size
25 mg
Description
3-Methyladenine inhibits autophagy by blocking autophagosome formation via inhibition of type III phosphatidylinositol 3-kinases (PI-3K). It protects 1321N1 astrocytoma cells against pyocyanin and hydroxyphenazine-induced toxicity. Inhibition of autophagy by 3-MA leads to enhanced apoptosis induced by a variety of agents including celastrol, cisplatin and sorafenib in several different cell lines.
Category
Proteins, Peptides and Small Molecules
Product Group
Inhibitors & Activators
CAS Number
5142-23-4
Application
Func
Shipping Temperature
BLUE ICE
Supplier URL
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