5-Lipoxygenase antibody [GT124...
- Article
- 5-Lipoxygenase antibody [GT1241]
- Product Number
- GTX02838-100UL
- Supplier
- GeneTex
- Size
- 100 ul
- Description
- This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
- Category
- Antibodies
- Product Group
- Recombinant Antibodies
- Application
- ICC, IF, IHC-P, WB
- Host
- Rabbit
- Species reactivity
- Human, Mouse, Rat
- Conjugate
- Unconjugated
- Clone ID
- GT1241
- Formulation
- PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
- Immunogen
- A synthesized peptide derived from human ALOX5
- Synonyms
- 5-LO; 5-LOX; 5LPG; arachidonic acid 5-lipoxygenase; leukotriene A4 synthase; LOG5; LOX-5; polyunsaturated fatty acid 5-lipoxygenase
- Unigene ID
- 240
- Gene Symbols
- ALOX5
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
![ICC/IF analysis of U2OS cells using GTX02838 5-Lipoxygenase antibody [GT1241].<br>Dilution : 1:100<br>Blue : DAPI for nuclear staining.](https://www.genetex.com/upload/website/prouct_img/normal/GTX02838/A2877_IF_01_(1072774)_w_23053123_270.webp)
Size: 100 ul
577.00 CHF