AntiSSeL Antibody
- Article
- AntiSSeL Antibody
- Product Number
- AB-0601-0250
- Supplier
- Life Sensors
- Size
- 250 ug
- Description
- A novel virulence factor was identified in Salmonella enterica serovar Typhimurium. This factor was determined to be a protein named SseL. SseL is translocated from the bacteria into the infected cell by a type III secretion system. SseL has deubiquitylating activity in vitro and infection of cells with a SseL mutant leads to the accumulation of ubiquitylated proteins. This mutant strain also fails to cause macrophage cell death, which has been implicated in the spread and systemic infection of Salmonella. Other serovars, including Typhi, Paratyphi A and Choleraesuis contain sequences encoding a protein nearly identical to SseL suggesting that deubiquitylating enzymes play an important role in the pathogenesis of other Salmonella serovars.
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Application
- WB
- Host
- Chicken/Avian
- Species reactivity
- Bacteria
- Synonyms
- STM2287; Deubiquitinating enzyme; Deubiquitinating protease; Salmonella secreted effector L
- Unigene ID
- 1253809
- Gene Symbols
- STM2287
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 250 ug
602.00 CHF