Anti Tyrosine Hydroxylase Anti...
- Article
- Anti Tyrosine Hydroxylase Antibody
- Product Number
- R1706-18
- Supplier
- Huabio
- Size
- 100 ul
- Description
- The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson's disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Application
- FC, IF, IHC-P, WB
- Host
- Rabbit
- Species reactivity
- Human, Mouse, Rat
- Conjugate
- Unconjugated
- Immunogen
- Synthetic peptide within Human Tyrosine Hydroxylase aa 1-50 / 528.
- Molecular Weight
- 58 kDa
- Synonyms
- dystonia 14; DYT14; DYT5b; TYH; tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; The
- Unigene ID
- 7054
- Gene Symbols
- TH
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page