Ataxin 3 is the disease protein in spinocerebellar ataxia type 3. Ataxin 3 contains a josephin domain and can cleave poly-ubiquitin chains in vitro. The proteolytic activity of Ataxin 3 regulates the amount of both total cellular ubiquitylation and ataxin 3 protein.
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
ELISA, WB
Host
Chicken/Avian
Species reactivity
Human
Synonyms
AT3; ataxin-3; ATX3; JOS; josephin; Machado-Joseph disease protein 1; MJD; MJD1; olivopontocerebellar ataxia 3; SCA3; spinocerebellar ataxia type 3 protein
