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Apolipoprotein B ELISA pair [L...

Article
Apolipoprotein B ELISA pair [LDL20/17/LDL11]
Product Number
GTX03048-1PAIR
Supplier
GeneTex
Size
1 pair
Description
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
Category
Antibodies
Product Group
Antibody Sets & Arrays
Application
ELISA, ELISA
Species reactivity
Human
Synonyms
apoB-100; apoB-48; apolipoprotein B (including Ag(x) antigen); apolipoprotein B-100; apolipoprotein B48; FCHL2; FLDB; LDLCQ4
Unigene ID
338
Gene Symbols
APOB
Shipping Temperature
BLUE ICE
Supplier URL
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