Apolipoprotein B ELISA pair [L...
- Article
- Apolipoprotein B ELISA pair [LDL20/17/LDL11]
- Product Number
- GTX03048-1PAIR
- Supplier
- GeneTex
- Size
- 1 pair
- Description
- This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
- Category
- Antibodies
- Product Group
- Antibody Sets & Arrays
- Application
- ELISA
- Species reactivity
- Human
- Synonyms
- apoB-100; apoB-48; apolipoprotein B (including Ag(x) antigen); apolipoprotein B-100; apolipoprotein B48; FCHL2; FLDB; LDLCQ4
- Unigene ID
- 338
- Gene Symbols
- APOB
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page