This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 2 and 7. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. [provided by RefSeq, Sep 2015]
A synthetic peptide corresponding to a sequence at the N-terminus of mouse Aurora B(72-87aa QNKQPFTIDNFEIGRP), different from the related rat sequence by two anino acids.