CDK2AP1 antibody
- Article
- CDK2AP1 antibody
- Product Number
- GTX55259-100UL
- Supplier
- GeneTex
- Size
- 100 ul
- Description
- The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Application
- WB
- Host
- Rabbit
- Species reactivity
- Human
- Conjugate
- Unconjugated
- Formulation
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of CDK2AP1. The exact sequence is proprietary.
- Synonyms
- CDK2-associated protein 1; cyclin-dependent kinase 2-associated protein 1; deleted in oral cancer 1; Deleted in oral cancer-1; DOC1; doc-1; DORC1; p12DOC-1; putative oral cancer suppressor; ST19
- Unigene ID
- 8099
- Gene Symbols
- CDK2AP1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
Size: 100 ul
505.00 CHF