This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Category
Antibodies
Product Group
Monoclonal Antibodies
Application
ELISA, FC, ICC, IF, IHC-P, WB
Host
Mouse
Species reactivity
Human, Mouse
Conjugate
Unconjugated
Clone ID
1A6
Formulation
PBS, 0.05% Sodium azide.
Immunogen
Purified recombinant fragment of human CDK2 expressed in E. Coli.
Synonyms
cdc2-related protein kinase; CDKN2; cell division protein kinase 2; cyclin-dependent kinase 2; p33 protein kinase; p33(CDK2)