The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Category
Antibodies
Product Group
Monoclonal Antibodies
Application
WB
Host
Mouse
Species reactivity
Human
Conjugate
Unconjugated
Clone ID
AT1G10
Formulation
PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen
The clone AT1G10 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CINP protein.
Synonyms
CDK2-interacting protein; cyclin-dependent kinase 2-interacting protein