GITR / NF-kB Luciferase Report...
- Article
- GITR / NF-kB Luciferase Reporter - Jurkat Cell Line
- Product Number
- 60546
- Supplier
- BPS Bioscience
- Size
- 2 vials
- Description
- This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene, TNFRSF18, CD357) and an NF-κB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene. The cells have been validated using purified human GITRL and anti-GITR neutralizing antibody.
- Category
- Cell Culture
- Product Group
- Primary Cells & Cell Lines
- Application
- Neut
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page