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GITR / NF-kB Luciferase Report...

Article
GITR / NF-kB Luciferase Reporter - Jurkat Cell Line
Product Number
60546
Supplier
BPS Bioscience
Size
2 vials
Description
This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene, TNFRSF18, CD357) and an NF-κB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene. The cells have been validated using purified human GITRL and anti-GITR neutralizing antibody.
Category
Cell Culture
Product Group
Primary Cells & Cell Lines
Application
Neut
Shipping Temperature
DRY ICE
Supplier URL
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