This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
IHC-P
Host
Rabbit
Species reactivity
Human
Conjugate
Unconjugated
Formulation
PBS, 0.1% Sodium azide.
Immunogen
Synthetic 19 amino acid peptide from 2nd cytoplasmic domain of human GPR132 / G2A.