HEK293/Human APP (GFP) Stable ...
- Article
- HEK293/Human APP (GFP) Stable Cell Line
- Product Number
- CHEK-ATP081-2VIALS
- Supplier
- Acro Biosystems
- Size
- 2 vials
- Description
- Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. It has three predominant splice variants: APP695, APP751, and APP770. The majority of APP is cleaved at the plasma membrane by the α-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with β-secretase cleavage by BACE1 on the N-terminal part of the Aβ domain, releasing sAPPβ from a membrane-anchored fragment named βCTF or C99, which is subsequently cleaved by γ-secretase to release Aβ. The price includes a surcharge of 350 CHF for Dry Ice delivery.
- Category
- Cell Culture
- Product Group
- Primary Cells & Cell Lines
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 2 vials
price on request