HEK293/Human APP (GFP) Stable ...
- Article
 - HEK293/Human APP (GFP) Stable Cell Line
 - Product Number
 - CHEK-ATP081-2VIALS
 - Supplier
 - Acro Biosystems
 - Size
 - 2 vials
 - Description
 - Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the α-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with β-secretase cleavage by BACE1 on the N-terminal part of the Aβ domain, releasing sAPPβ from a membrane-anchored fragment named βCTF or C103, which is subsequently cleaved by γ-secretase to release Aβ.
 - Category
 - Cell Culture
 - Product Group
 - Primary Cells & Cell Lines
 - Shipping Temperature
 - DRY ICE
 - Supplier URL
 - Visit supplier product page