HEK293/Human Alpha-synuclein (...
- Article
- HEK293/Human Alpha-synuclein (GFP) Stable Cell Line
- Product Number
- CHEK-ATP085-2VIALS
- Supplier
- Acro Biosystems
- Size
- 2 vials
- Description
- Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration. The price includes a surcharge of 350 CHF for Dry Ice delivery.
- Category
- Cell Culture
- Product Group
- Primary Cells & Cell Lines
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page