Human APE1 protein, T7 tag
- Article
- Human APE1 protein, T7 tag
- Product Number
- GTX67225-PRO-50UG
- Supplier
- GeneTex
- Size
- 50 ug
- Description
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein. [provided by RefSeq, Jul 2008]
- Category
- Molecular Biology
- Product Group
- Molecular Biology Enzymes
- Conjugate
- Unconjugated
- Formulation
- 20mM Tris-HCl, 200mM NaCl, 10% Glycerol, 2mM DTT, no preservative.
- Synonyms
- AP endonuclease class I; AP lyase; APE; APE1; APEN; APEX; APEX nuclease (multifunctional DNA repair enzyme) 1; apurinic/apyrimidinic (abasic) endonuclease; apurinic-apyrimidinic endonuclease 1; APX; deoxyribonuclease (apurinic or apyrimidinic); DNA-(apurinic or apyrimidinic site) endonuclease; DNA-(apurinic or apyrimidinic site) lyase; HAP1; protein REF-1; redox factor-1; REF1; APEX nuclease; REF-1
- Unigene ID
- 328
- Gene Symbols
- APEX1
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 50 ug
414.00 CHF