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Human Ab1-40 Antibody Pair

Article
Human Ab1-40 Antibody Pair
Product Number
ES-015-1PAIR
Supplier
Absea
Size
1 pair
Description
Amyloid-beta (1-40), abbreviated as Aβ(1-40), is a 40-residue peptide derived from the amyloid precursor protein (APP) and is involved in the pathogenesis of Alzheimer's disease (AD). It is one of the two main C-terminal variants of the amyloid-beta peptide, along with Aβ(1-42). Both Aβ(1-40) and Aβ(1-42) form aggregates and deposits in the AD brain, contributing to the formation of senile plaques. Unaggregated soluble Aβ(1-40) can also exhibit toxic effects and influence behavior and memory. Additionally, Aβ(1-40) has been shown to interact with synaptic structures such as postsynaptic density-95 (PSD-95), leading to its degradation and affecting synaptic function.
Category
Antibodies
Product Group
Antibody Sets & Arrays
Application
ELISA
Host
Mouse
Species reactivity
Human
Purity
≥85%
Formulation
phosphate buffered saline
Shipping Temperature
BLUE ICE
Supplier URL
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