Human Ab1-40 Antibody Pair
- Article
- Human Ab1-40 Antibody Pair
- Product Number
- ES-016-1PAIR
- Supplier
- Absea
- Size
- 1 pair
- Description
- Amyloid-beta (1-40), abbreviated as Aβ(1-40), is a 40-residue peptide derived from the amyloid precursor protein (APP) and is involved in the pathogenesis of Alzheimer's disease (AD). It is one of the two main C-terminal variants of the amyloid-beta peptide, along with Aβ(1-42). Both Aβ(1-40) and Aβ(1-42) form aggregates and deposits in the AD brain, contributing to the formation of senile plaques. Unaggregated soluble Aβ(1-40) can also exhibit toxic effects and influence behavior and memory. Additionally, Aβ(1-40) has been shown to interact with synaptic structures such as postsynaptic density-95 (PSD-95), leading to its degradation and affecting synaptic function.
- Category
- Antibodies
- Product Group
- Antibody Sets & Arrays
- Application
- ELISA
- Host
- Mouse
- Species reactivity
- Human
- Purity
- ≥85%
- Formulation
- phosphate buffered saline
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page