Human Ab1-42 Antibody Pair
- Article
- Human Ab1-42 Antibody Pair
- Product Number
- ES-020-1PAIR
- Supplier
- Absea
- Size
- 1 pair
- Description
- The Aβ1-42 peptide is a 42-amino acid fragment cleaved from the amyloid precursor protein (APP) by secretase enzymes. It is the longer and more amyloidogenic form of the Aβ peptide, compared to the more common Aβ1-40 form. Aβ1-42 has a greater tendency to aggregate and form amyloid fibrils and plaques in the brain, which is a hallmark pathological feature of Alzheimer's disease. Increased production and accumulation of Aβ1-42 relative to Aβ1-40 is associated with genetic mutations, certain ApoE alleles, and other as-yet undiscovered factors that increase the risk of Alzheimer's disease. Measurement of the Aβ1-42 peptide in cerebrospinal fluid (CSF) is used as a biomarker for Alzheimer's disease, as decreased CSF Aβ1-42 levels indicate increased brain deposition of the peptide.The Aβ1-42/Aβ1-40 ratio in CSF is considered a more sensitive and specific marker of Alzheimer's pathology than Aβ1-42 alone.
- Category
- Antibodies
- Product Group
- Antibody Sets & Arrays
- Application
- ELISA
- Host
- Mouse
- Species reactivity
- Human
- Purity
- ≥85%
- Formulation
- phosphate buffered saline
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
![Microtiter wells were coated with K70013_6H1 at µg/mL as the capture antibody. Recommbinant Beta Amyloid 1-42 protein (Cat #: PE-002) was used as the antigen. Biotin conjugated Beta Amyloid 1-42 Antibody [K92011_13F10] was used as the detection antibody. Result: K70013_6H1 and K92011_13F10 can be used as a matched antibody pair to detect and quantify the concentration of Human Beta Amyloid 1-42 with high specificity.](https://www.absea.bio/product-images/ES-020_Sandwich ELISA_10.jpg?v=0.21395322587319154)
Size: 1 pair
1'180.00 CHF