Human DNase I protein, His tag
- Article
- Human DNase I protein, His tag
- Product Number
- GTX00172-PRO-10UG
- Supplier
- GeneTex
- Size
- 10 ug
- Description
- This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Category
- Molecular Biology
- Product Group
- Molecular Biology Enzymes
- Application
- Func
- Conjugate
- Unconjugated
- Formulation
- Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
- Synonyms
- deoxyribonuclease I; deoxyribonuclease-1; DNase I, lysosomal; DNL1; Dornase alfa; DRNI; human urine deoxyribonuclease I
- Unigene ID
- 1773
- Gene Symbols
- DNASE1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
Size: 10 ug
343.00 CHF