Human GPI protein, His tag (ac...
- Article
- Human GPI protein, His tag (active)
- Product Number
- GTX67023-PRO-20UG
- Supplier
- GeneTex
- Size
- 20 ug
- Description
- This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Proteins
- Application
- Func
- Conjugate
- Unconjugated
- Formulation
- 20mM Tris-HCl, 10% Glycerol, 1mM DTT, no preservative.
- Synonyms
- AMF; autocrine motility factor; glucose-6-phosphate isomerase; GNPI; hexose monophosphate isomerase; hexosephosphate isomerase; neuroleukin; NLK; oxoisomerase; PGI; PHI; phosphoglucose isomerase; phosphohexomutase; phosphohexose isomerase; phosphosaccharomutase; SA36; SA-36; sperm antigen-36; Sperm antigen 36
- Unigene ID
- 2821
- Gene Symbols
- GPI
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 20 ug
290.00 CHF