Human IL-17 RA/IL-17 RC (Luc) ...
- Article
- Human IL-17 RA/IL-17 RC (Luc) HEK293 Reporter Cell
- Product Number
- CHEK-ATF133-2VIALS
- Supplier
- Acro Biosystems USD
- Size
- 2 vials
- Description
- Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways, ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.
- Category
- Cell Culture
- Product Group
- Primary Cells & Cell Lines
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 2 vials
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