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Human MASP2 protein, His tag

Article
Human MASP2 protein, His tag
Product Number
GTX00122-PRO-10UG
Supplier
GeneTex
Size
10 ug
Description
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Category
Proteins, Peptides and Small Molecules
Product Group
Kinases & Other Enzymes
Application
Func
Conjugate
Unconjugated
Formulation
Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Synonyms
mannan binding lectin serine peptidase 2; mannan-binding lectin serine peptidase 1 pseudogene 1; mannan-binding lectin serine protease 1 pseudogene 1; mannan-binding lectin serine protease 2; mannose-binding lectin associated protein 19; mannose-binding lectin-associated serine protease 2; mannose-binding protein-associated serine protease 2; MAP19; MAP-2; MASP1P1; MASP-2; MBL-associated plasma protein of 19 kD; small MBL-associated protein; sMAP; MBL-associated serine protease 2
Unigene ID
10747
Gene Symbols
MASP2
Shipping Temperature
BLUE ICE
Supplier URL
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