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Human RNAse H2A protein, His t...

Article
Human RNAse H2A protein, His tag
Product Number
GTX68166-PRO-100UG
Supplier
GeneTex
Size
100 ug
Description
The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
Category
Molecular Biology
Product Group
Molecular Biology Enzymes
Conjugate
Unconjugated
Synonyms
AGS4; aicardi-Goutieres syndrome 4 protein; JUNB; ribonuclease H2 subunit A; ribonuclease H2, large subunit; ribonuclease HI large subunit; ribonuclease HI subunit A; RNase H(35); RNase H2 subunit A; RNase HI large subunit; RNASEHI; RNHIA; RNHL; THSD8
Unigene ID
10535
Gene Symbols
RNASEH2A
Shipping Temperature
BLUE ICE
Supplier URL
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