Human RNAse H2A protein, His t...
- Article
- Human RNAse H2A protein, His tag
- Product Number
- GTX68166-PRO-100UG
- Supplier
- GeneTex
- Size
- 100 ug
- Description
- The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
- Category
- Molecular Biology
- Product Group
- Molecular Biology Enzymes
- Conjugate
- Unconjugated
- Formulation
- 20mM Tris-HCl, 0.4M Urea, 10% Glycerol, no preservative.
- Synonyms
- AGS4; aicardi-Goutieres syndrome 4 protein; JUNB; ribonuclease H2 subunit A; ribonuclease H2, large subunit; ribonuclease HI large subunit; ribonuclease HI subunit A; RNase H(35); RNase H2 subunit A; RNase HI large subunit; RNASEHI; RNHIA; RNHL; THSD8
- Unigene ID
- 10535
- Gene Symbols
- RNASEH2A
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 100 ug
557.00 CHF