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PACAP (1-38) (human, mouse, ov...

Article
PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt)
Product Number
24770-500UG
Supplier
Cayman Chemical
Size
500 ug
Description
A PACAP receptor agonist (IC50s = 4, 2, and 1 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors), binds to PACAP receptors in rat brain membrane (IC50 = 4.45 nM) and to SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 3.6, 13, and 4.7 nM, respectively), stimulates cAMP accumulation in H-SY5Y, SK-N-MC, and T47D cells (EC50s = 0.37, 0.26, and 0.73 nM, respectively), induces vasodilation of pial arterioles by 43% in newborn pigs (1 µM)
Category
Proteins, Peptides and Small Molecules
Product Group
Inhibitors & Activators
Purity
≥95%
Formulation
A lyophilized powder
Molecular Weight
4534.3
Shipping Temperature
DRY ICE
Supplier URL
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