PDE10A-HEK293 Recombinant Cell...
- Article
- PDE10A-HEK293 Recombinant Cell line
- Product Number
- 60410
- Supplier
- BPS Bioscience
- Size
- 2 vials
- Description
- Recombinant HEK293 cell line expressing human PDE10A2 (phosphodiesterase 10A, accession number NM_006661). N-terminal His-tagged human PDE10A2 has been stably expressed in a human embryonic kidney (HEK293) cell line. PDE10A2 expression was confirmed by Western blotting. The function of PDE10A2 was confirmed by cAMP detection assay. Forskolin is commonly used to raise levels of intracellular cyclic AMP (cAMP). When HEK293 cells are activated by forskolin, cAMP levels are upregulated in parental cells, whereas cells overexpressing PDE10A show reduction in cAMP accumulation. Inhibition of PDE10A activity restores cAMP levels.. Please note that purchase of cell lines from BPS requires a limited use license for non-commercial use. The license agreement must be signed by the end user prior to the purchase. You can view the license agreement here: https://www.lubio.ch/supplier/bps-bioscience#c10947
- Category
- Cell Culture
- Product Group
- Primary Cells & Cell Lines
- Synonyms
- 3',5' cAMP/cGMP phosphodiesterase; ADSD2; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); HSPDE10A; IOLOD; LINC00473; PDE10A19; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7)
- Unigene ID
- 10846
- Gene Symbols
- PDE10A
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 2 vials
price on request