PI(3 4 5)P3 diC8 (Phosphatidylinositol 3 4 5-trisphosphate diC8) is a synthetic purified dioctanoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dioctanoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (8:0/8:0) PI(3 4 5)P3 C8 or PIP3Bulk discounts available please email echelon@echelon-inc.com for information. Powered by Bioz See more details on Bioz
