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Radicicol

Article
Radicicol
Product Number
SIH-117A
Supplier
StressMarq Biosciences
Size
1 mg
Description
Radicicol inhibits src (IC50=0.27µM) and src-like kinases(1), leading to hypophosphorylation of retinoblastoma tumor suppressor protein(2). It causes morphological reversion of ras-transformed cells(3) and leads to selective depletion of Raf kinase(4). It also displays anti-angiogenic activity(5), and binds to and inhibits Hsp 90 molecular chaperone(6). It binds more strongly to Hsp90 than to GRP94. It also binds to yeast HSP90, E. coli HtpG and TRAP-1. Looking for more information on HSP90? Visit our new HSP90 Scientific Resource Guide at http://www.HSP90.ca.
Category
Proteins, Peptides and Small Molecules
Product Group
Inhibitors & Activators
CAS Number
12772-57-5
Purity
97%
Molecular Weight
364.8
Shipping Temperature
RT
Supplier URL
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