Recombinant PRDM14 protein
- Article
- Recombinant PRDM14 protein
- Product Number
- 31397
- Supplier
- Active Motif
- Size
- 20 ug
- Description
- Recombinant PRMT6 (accession number NP_060607.2) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 43.7 kDa. PRMT6 (Protein Arginine Methyltransferase 6, HRMT1L6, ANM6) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT6 preferentially methylates arginine residues present in GAR (glycine and arginine-rich) domains. PRMT6 asymmetrically dimethylates histone H3 at Arg2, which is mutually exclusive to methylation at lysine 4 (associated with transcriptional activation), and thus PRMT6 serves as a transcriptional repressor in this context. It can also symmetrically dimethylate H2A and H4 at Arg3 and serves as a coactivator of transcription in concert with nuclear receptors. Recombinant PRMT6 can be used to study enzyme kinetics and perform inhibitor screening assays.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Kinases & Other Enzymes
- Purity
- 90% pure by SDS-PAGE
- Formulation
- Full length recombinant PRMT6 protein was supplied in 25 mM Hepes-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100, 0.5 mM TCEP.
- Molecular Weight
- 6 43.7 kDa
- Shipping Temperature
- DRY ICE
- Supplier URL
- Visit supplier product page
Size: 20 ug
571.00 CHF