Shh antibody [10H6]
- Article
- Shh antibody [10H6]
- Product Number
- GTX83651-100UL
- Supplier
- GeneTex
- Size
- 100 ul
- Description
- Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction.
- Category
- Antibodies
- Product Group
- Monoclonal Antibodies
- Application
- ICC, IF, WB
- Host
- Mouse
- Species reactivity
- Dog, Human, Non-human Primate, Rat
- Conjugate
- Unconjugated
- Clone ID
- 10H6
- Formulation
- PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 24-197 of human SHH (NP_000184) produced in E.coli.
- Synonyms
- HHG1; HLP3; HPE3; MCOPCB5; shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; ShhNC; SMMCI; sonic hedgehog homolog; sonic hedgehog protein; TPT; TPTPS; HHG-1
- Unigene ID
- 6469
- Gene Symbols
- SHH
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
![WB analysis of HEK293T cells transfected with Shh plasmid (Right) or empty vector (Left) for 48 hrs using GTX83651 Shh antibody [10H6].<br>Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX83651/GTX83651_3791_WB_w_23061420_970.webp)
Size: 100 ul
743.00 CHF