Sulfo-NHS-LC-Biotin
- Article
- Sulfo-NHS-LC-Biotin
- Product Number
- A8003-100MG
- Supplier
- Apex Bio
- Size
- 100 mg
- Description
- Sulfo-NHS-LC-biotin (Sulfosuccinimidyl 6-(biotinamido) Hexanoate) is an amine-reactive biotinylation agent. As a water-soluble analog of NHS-LC-biotin, Sulfo-NHS-LC-biotin contains a negatively charged sulfonate group on the NHS ring structure, which creates sufficient polarity within the molecule and allows it to be directly added into aqueous reactions without prior dissolution of organic solvents. Sulfo-NHS-LC-biotin covalently binds to amine groups in proteins and other molecules through its NHS ester forming an amide linkage and releasing N-Hydroxysuccinimide. Sulfo-NHS-LC-biotin has a greater length (22.4 A) between a covalently modified molecule and the bicyclic biotin rings than NHS-biotin (13.5 A), which provides the probes a greater opportunity to reach the binding sites deeply buried inside the surface plane of proteins.ReferenceBioconjugate Techniques , 2nd ed. By Greg T.Hermanson (Pierce Biotechnology, Thermo Fisher Scientific, Rockford, IL). Academic Press (an imprint of Elsevier): London, Amsterdam, Burlington, San Diego . 2008. ISBN 978-0-12-370501-3.
- Category
- Lab Reagents & Chemicals
- Product Group
- Biochemicals
- CAS Number
- 127062-22-0
- Purity
- 98%
- Molecular Weight
- 556.6
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page
Size: 100 mg
238.00 CHF