Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
Category
Antibodies
Product Group
Polyclonal Antibodies
Application
FACS, ICC, IF, WB
Host
Rabbit
Species reactivity
Human, Rat
Conjugate
Unconjugated
Formulation
4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, no preservatives.
Immunogen
E.coli-derived human TRPV1 recombinant protein (Position: E107-A800).