anti HIgG(Fc)Fab-C-MMAE ADC
- Article
- anti HIgG(Fc)Fab-C-MMAE ADC
- Product Number
- ADC-AA-011
- Supplier
- Creative Biolabs
- Size
- 50 ug
- Description
- This ADC product is comprised of a Fab fragment of an anti-human IgG Fc specific polyclonal antibody conjugated via a cleavable linker to MMAE. The antibody portion is a Fab fragment of a secondary antibody and the drug portion, MMAE, is a cytotoxic small molecule which binds to tubulins, interrupts microtubule dynamics, and induces cell death. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates.
- Category
- Antibodies
- Product Group
- Polyclonal Antibodies
- Shipping Temperature
- DRY ICE