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anti TGF beta antibody [2C5]

Article
anti TGF beta antibody [2C5]
Product Number
ARG10003-100UG
Supplier
Arigo Biolaboratories
Size
100 ug
Description
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]
Category
Antibodies
Product Group
Monoclonal Antibodies
Application
ELISA, WB
Host
Mouse
Species reactivity
Human
Conjugate
Unconjugated
Clone ID
2C5
Formulation
0.01M PBS (pH 7.0)
Immunogen
TGF-b from human platelets
Synonyms
CED; DPD1; IBDIMDE; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; TGFB; TGFbeta; TGF-beta1; TGF-beta-1; transforming growth factor beta1; transforming growth factor beta-1 proprotein
Unigene ID
7040
Gene Symbols
TGFB1
Shipping Temperature
BLUE ICE
Supplier URL
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