A monoterpene ketone with diverse biological activities, inhibits ACh-induced currents in Xenopus oocytes expressing human α7 nAChRs (IC50 = 27 µM), reduces GABA-induced current amplitude in HEK293 cells expressing α1β2δ subunit-containing GABA receptors at 100 and 300 µM, reduces levels of FCV-F9 and MNV-1 in a plaque formation assay at 25 mM, impairs nicotine-induced enhancement of long-term potentiation in the dentate gyrus in rats at 1.25 mg/kg, i.p., inhibits lung metastasis and increases survival in a B16/F10 murine melanoma model at 1 mg/kg
