4E-BP1 (phospho Thr37/Thr46) a...
- Article
- 4E-BP1 (phospho Thr37/Thr46) antibody [HL3276]
- Product Number
- GTX640930-100UL
- Supplier
- GeneTex
- Size
- 100 ul
- Description
- This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
- Category
- Antibodies
- Product Group
- Recombinant Antibodies
- Application
- WB
- Host
- Rabbit
- Species reactivity
- Human, Mouse
- Conjugate
- Unconjugated
- Clone ID
- HL3276
- Formulation
- PBS, no preservative.
- Immunogen
- Carrier-protein conjugated synthetic peptide surrounding phospho Thr37/Thr46 of human 4E-BP1. The exact sequence is proprietary.
- Synonyms
- 4EBP1; 4E-BP1; BP-1; eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; phosphorylated heat- and acid-stable protein regulated by insulin 1
- Unigene ID
- 1978
- Gene Symbols
- EIF4EBP1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page