53BP1 antibody [HMV324] HistoM...
- Article
- 53BP1 antibody [HMV324] HistoMAX
- Product Number
- GTX640556-500UL
- Supplier
- GeneTex
- Size
- 500 ul
- Description
- This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
- Category
- Antibodies
- Product Group
- Recombinant Antibodies
- Application
- IHC-P
- Host
- Rabbit
- Species reactivity
- Human
- Conjugate
- Unconjugated
- Clone ID
- HMV324
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human 53BP1. The exact sequence is proprietary.
- Synonyms
- 53BP1; p202; p53-binding protein 1; p53BP1; TDRD30; TP53-binding protein 1; tumor protein 53-binding protein, 1; tumor suppressor p53-binding protein 1
- Unigene ID
- 7158
- Gene Symbols
- TP53BP1
- Shipping Temperature
- BLUE ICE
- Supplier URL
- Visit supplier product page